The latest data from UKHSA shows that vaccinated women who gave birth between January and October 2021 had a very similar low risk of stillbirth, low birthweight and premature birth compared to women who were not vaccinated in pregnancy. Read more facts and figures in the press release here.
Tag Archives: Covid-19
COVID-19 antivirals: reporting to the UK COVID-19 Antivirals Pregnancy Registry
As the safety of COVID-19 antivirals in pregnancy has not been established, MHRA requests reports of any pregnancies which occur during use of an antiviral, including paternal use, to the UK COVID-19 Antivirals Pregnancy Registry. This advice applies to molnupiravir (Lagevrio▼), the combination of PF-07321332 (nirmatrelvir) plus ritonavir (Paxlovid▼), and remdesivir (Veklury▼). Full details here
Maximising access to COVID-19 vaccination in pregnancy
NHS England has written to ask maternity service leads to co-ordinate with Vaccination Programme leads so that every woman attending a maternity service has easy, timely access to vaccine confidence conversations and co-located vaccination offers.
Read the letter from 25 January 2022 here, and also the RCOG / RCM updated Information sheet and decision aid it links to: (Updated Monday 20 December 2021)
RCOG Coronavirus (COVID-19) Infection in Pregnancy Information for healthcare professionals Version 14.3
The latest version of RCOG’s guidance was made available on 11 January 2022, previously having been updated in December 2021.
v14.2 (December 2021) Minor updates included:
• Quick reference summary: replaced by flowchart
• Section 2: Minor updates of vaccination safety data
• Section 6: Clarification of Ronapreve dose to 2.4g, restoration of dexamethasone dose to 12mg intramuscular x2 (24 hours apart), advice not to use Molupiravir outside a trial settings and on neonatal BCG after maternal administration of Tocolizumab.
• Section 7: Update of postnatal neonatal guidance in line with BAPM
• Addition of appendix IV: Example of a telephone triage tool for symptomatic women with suspected or confirmed COVID-19
Also included is a Treatment of COVID-19 in pregnant patients one page sheet
Version 14.3 January 2022 minor updates include:
• Section 2: Minor updates on omicron vaccine efficacy.
• Section 6: Recognition that monoclonal antibody advice is
changing rapidly, with external links for clarification. Clarification
of recommended steroid preparations, with addition of
methylprednisolone if preferred.
• Section 7: Aligning with BAPM isolation advice.
View the updated guidance here
COVID-19 vaccination: women of childbearing age, currently pregnant or breastfeeding
UKSA have updated their ‘COVID-19 vaccination: a guide on pregnancy and breastfeeding’ View the updated guidance here
COVID-19 vaccination in pregnancy surveillance
UK Health Security Agency working with the Medicines & Healthcare products Regulatory Agency have published the protocol for the national surveillance and safety analysis of coronavirus (COVID-19) vaccination in pregnancy. View the document here
Coronavirus (COVID-19) infection and pregnancy
RCOG have updated their guidance to Version 14.1: updated November 2 2021.
Changes include a new section 2, “COVID-19 Vaccination in pregnancy” and information about ivermectin added to the Quick Reference Section
View the updated guidance here
Using Tocilizumab or Sarilumab for hospitalised patients with COVID-19 who are pregnant
This page from the Specialist Pharmacy Service signposts to current guidance on this off-label use of the two medicines from the UK Royal College of Obstetricians and Gynaecologists and UKTIS. Healthcare professionals are encouraged to contact UKTIS should they be considered for use. See also Using Tocilizumab or Sarilumab for hospitalised patients with COVID-19 who are breastfeeding and Breastfeeding with COVID-19 infection 12 October 2021
RCOG – Coronavirus (COVID-19) Infection in Pregnancy v14
RCOG published the updated version of their guidance on 25th August 2021.
It adds a new quick reference section, adds new evidence taking into account the Delta variant, and adds a new section on vaccination in pregnancy.
Read the full guidance here
COVID-19 in pregnancy
NHS England have written to all maternity services to outline research suggesting Delta variant is associated with increased risk of severe illness among hospitalised pregnant women, vs other variants, and highlights importance of 2 doses of vaccine to achieve high levels of protection and increasing uptake in pregnant women.
as well as ensuring that information and materials are available for women in all antenatal and primary care settings, the letter recommended that providers encourage all maternity staff to receive the protections offered by vaccination.
May data from the SIREN study suggested that while generally high (84.5%) ,midwives had the lowest rate of vaccination among health care professional groups.
Read the letter in full here
COVID-19 vaccinations and pregnancy poster and social media cards
Maternal, Newborn and Infant Clinical Outcome Review Programme Rapid report, 2021: Learning from SARS-CoV-2 related and associated maternal deaths in the UK
This new MBRRACE report includes lessons identified from the care of women who died between 1 June 2020 and 31 March 2021, following a positive test for SARS-CoV-2 infection, or in whom SARS-CoV-2 infection was diagnosed at autopsy, as well as from the deaths of women whose care or engagement with care was influenced by changes as a consequence of the pandemic.
Read the full report here
Maternity & Obstetrics 